Association of Vertigo and Nausea and Vomiting of Pregnancy


  • Yasemin Hamlacı Başkaya Sakarya University, Faculty of Health Sciences, Sakarya, Turkey.
  • Kevser İlçioğlu Sakarya University, Faculty of Health Sciences, Sakarya, Turkey.
  • Alaattin Ünsal Eskisehir Osmangazi University, Medical Faculty, Public Health Department, Eskisehir, Turkey.



Pregnancy, vertigo, PUQE test


Objective: To determine the prevalence of vertigo during pregnancy, to review some variables believed to be associated, and to determine the association between vertigo and nausea and vomiting.

Methods: This study is a cross-sectional study conducted on pregnant women between September 3 and November 30, 2020. The study group consisted of 560 pregnant women who agreed to take part in the study. Chi-square test and Logistic Regression Analysis (Stepwise Backward Wald Regression), Mann-Whitney U test and Kruskal-Wallis Analysis were used for analysis. P≤0.05 was accepted as statistical significance value.

Results: The number of pregnant women with a history of vertigo was found to be 208 (37.1%). The symptoms that were most commonly reported by those with a history of vertigo were nausea and vomiting, headache and stumbling while walking, respectively. It was determined that the level of nausea and vomiting was higher in women with vertigo but there was no difference between the type and severity of vertigo and the level of nausea and vomiting.

Conclusion: Vertigo is one of the important health problems in pregnancy. It was determined that the level of nausea and vomiting was higher in women with vertigo. Nausea and vomiting are the most common symptoms accompanying vertigo.


Tan EK, Tan EL. Alterations in physiology and anatomy during pregnancy. Best practice & research Clinical obstetrics & gynaecology. 2013;27(6):791-802.

Salvati A, Apa R, Loperfido A, Scarano E, Paludetti G, Tropea A, et al. Management of vertigo in pregnancy. Italian Journal of Gynaecology and Obstetrics. 2020;32(1):49-55.

Schmidt PM, Flores F, Rossi AG, Silveira AF. Hearing and vestibular complaints during pregnancy. Brazilian Journal of Otorhinolaryngology. 2010;76(1):29-33.

Bhavana G, Kumar K, Anupriya E. Assessment of otolith function using vestibular evoked myogenic potential in women during pregnancy. Brazilian Journal of Otorhinolaryngology. 2020.

Kara İ, Yıldız MG, Gümüştakım RŞ, Doğaner A, Sağıroğlu S, Bilal N, et al. Evalution of Family Physician’s Awareness of Vertigo: A Cross-sectional Study. Turkish Journal of Family Practice. 2021;25(2):59-65.

Wipperman J. Dizziness and vertigo. Primary Care: Clinics in Office Practice. 2014;41(1):115-31.

Murthy VA, Krishna K. Hearing loss in pregnancy. Indian Journal of Otolaryngology & Head and Neck Surgery. 2013;65(1):1-2.

Liang Y-X, Liu L, Jin Z-Y, Liang X-H, Fu Y-S, Gu X-W, et al. The high concentration of progesterone is harmful for endometrial receptivity and decidualization. Scientific Reports. 2018;8(712):1-12.

Swain SK, Pati BK, Mohanty JN. Otological manifestations in pregnant women-A study at a tertiary care hospital of eastern India. Journal of Otology. 2020;15(3):103-6.

Laitinen L, Nurmi M, Ellilä P, Rautava P, Koivisto M, Polo-Kantola P. Nausea and vomiting of pregnancy: associations with personal history of nausea and affected relatives. Archives of Gynecology and Obstetrics. 2020;302(4):947-55.

Şimşek Y, Şimşek G, Bayar Muluk N, Arıkan OK. Olfactory dysfunction and oxidative stress in pregnant women with hyperemesis gravidarum. Archives of Gynecology and Obstetrics. 2021;304(3):657-61.

Black FO. Maternal susceptibility to nausea and vomiting of pregnancy: is the vestibular system involved? American journal of obstetrics and gynecology. 2002;186(5):204-9.

Koren G, Piwko C, Ahn E, Boskovic R, Maltepe C, Einarson A, et al. Validation studies of the Pregnancy Unique-Quantification of Emesis (PUQE) scores. Journal of Obstetrics and Gynaecology. 2005;25(3):241-4.

King TL, Murphy PA. Evidence-based approaches to managing nausea and vomiting in early pregnancy. Journal of midwifery & women's health. 2009;54(6):430-44.

Sucu M, Büyükkurt S, Evrüke İ, Demir S, Özgünen F, Kadayıfçı O. The role of PUQE (Pregnancy-Unique Quantification of Emesis and Nausea) in evaluation of the indications for inpatient therapy in pregnants with nausea and vomiting. Turkiye Klinikleri J Gynecol Obst. 2009;19(6):317-21.

Jeong S-H. Benign paroxysmal positional vertigo risk factors unique to perimenopausal women. Frontiers in Neurology. 2020;11(589605):1-6.

Lindell E, Karlsson T, Kollén L, Johansson M, Finizia C. Benign paroxysmal positional vertigo and vestibular impairment among older adults with dizziness. Laryngoscope Investigative Otolaryngology. 2021;6(3):488-95.

Çoban K, Yiğit N, Aydın E. Benign paroxysmal positional vertigo in pregnancy. Turkish archives of otorhinolaryngology. 2017;55(2):83.

Agampodi SB, Wickramasinghe ND, Horton J, Agampodi TC. Minor ailments in pregnancy are not a minor concern for pregnant women: a morbidity assessment survey in rural Sri Lanka. PloS one. 2013;8(5):e64214.

Chen J, Zhao W, Yue X, Zhang P. Risk factors for the occurrence of benign paroxysmal positional vertigo: a systematic review and meta-analysis. Frontiers in neurology. 2020;11:506.

Wassermann A, Finn S, Axer H. Age-associated characteristics of patients with chronic dizziness and vertigo. Journal of geriatric psychiatry and neurology. 2021:1-6.

Rashid ZS, Abed BJ. Relationship between the Effect of Severity Vertigo and Demographic Characteristic for Iraqi Patients. Indian Journal of Forensic Medicine & Toxicology. 2021;15(3):785-90.

Li S, Wang Z, Liu Y, Cao J, Zheng H, Jing Y, et al. Risk factors for the recurrence of benign paroxysmal positional vertigo: a systematic review and meta-analysis. Ear, Nose & Throat Journal. 2020:1-23.

Wu PH, Cheng PW, Young YH. Inner ear disorders in 68 pregnant women: a 20‐year experience. Clinical Otolaryngology. 2017;42(4):844-6.

Frosolini A, Marioni G, Gallo C, de Filippis C, Lovato A. Audio-vestibular disorders and pregnancy: A systematic review. American Journal of Otolaryngology. 2021;42(5):103136.

Chen J-J, Chang H-F, Chen D-L. Vestibular Migraine in a Female With Unexpected Pregnancy. Archives of Neuroscience. 2016;3(1):e22924.

Mgbe RB, Umana AN, Adekanye AG, Offiong ME. Ear nose and throat changes observed in pregnancy in Calabar Nigeria. Global Journal of Pure and Applied Sciences. 2017;23(2):355-9.

Lagadec N, Steinecker M, Kapassi A, Magnier AM, Chastang J, Robert S, et al. Factors influencing the quality of life of pregnant women: a systematic review. BMC pregnancy and childbirth. 2018;18(455):1-14.

Tian R, MacGibbon K, Martin B, Mullin P, Fejzo M. Analysis of pre-and post-pregnancy issues in women with hyperemesis gravidarum. Autonomic Neuroscience. 2017;202:73-8.

Lewandowska M, Więckowska B, Sajdak S. Pre-pregnancy obesity, excessive gestational weight gain, and the risk of pregnancy-induced hypertension and gestational diabetes mellitus. Journal of clinical medicine. 2020;9(6):1980.

Wang Y-X, Wang S, Mitsunami M, Manson JE, Rich-Edwards JW, Wang L, et al. Pre-pregnancy menstrual cycle regularity and length and the risk of gestational diabetes mellitus: prospective cohort study. Diabetologia. 2021;64(11):2415-24.

Wei Y-M, Yang H-X, Zhu W-W, Liu X-Y, Meng W-Y, Wang Y-Q, et al. Risk of adverse pregnancy outcomes stratified for pre-pregnancy body mass index. The Journal of Maternal-Fetal & Neonatal Medicine. 2016;29(13):2205-9.

Wesołowska E, Jankowska A, Trafalska E, Kałużny P, Grzesiak M, Dominowska J, et al. Sociodemographic, lifestyle, environmental and pregnancy-related determinants of dietary patterns during pregnancy. International journal of environmental research and public health. 2019;16(5):754.

Chatterjee N, Fernandes G. ‘This is normal during pregnancy’: a qualitative study of anaemia-related perceptions and practices among pregnant women in Mumbai, India. Midwifery. 2014;30(3):e56-e63.

Ding J, Liu L, Kong W-K, Chen X-B, Liu X. Serum levels of 25-hydroxy vitamin D correlate with idiopathic benign paroxysmal positional vertigo. Bioscience reports. 2019;39(4).

Han W, Fan Z, Zhou M, Guo X, Yan W, Lu X, et al. Low 25-hydroxyvitamin D levels in postmenopausal female patients with benign paroxysmal positional vertigo. Acta oto-laryngologica. 2018;138(5):443-6.

Yang H, Gu H, Sun W, Li Y, Wu H, Burnee M, et al. Estradiol deficiency is a risk factor for idiopathic benign paroxysmal positional vertigo in postmenopausal female patients. The Laryngoscope. 2018;128(4):948-53.

Tulmaç ÖB, Kılıç R, Yaman S, Aktulum F, Şimşek G, Erdinç S. Evaluation of the vestibular system with video head impulse test in pregnant women with hyperemesis gravidarum. Journal of Obstetrics and Gynaecology Research. 2021;47(1):96-102.

Robbins MS, Farmakidis C, Dayal AK, Lipton RB. Acute headache diagnosis in pregnant women: a hospital-based study. Neurology. 2015;85(12):1024-30.




How to Cite

Hamlacı Başkaya, Y., İlçioğlu, K., & Ünsal, A. (2023). Association of Vertigo and Nausea and Vomiting of Pregnancy. Journal of Contemporary Medical Sciences, 9(1).