Can latent toxoplasmosis lead to Alzheimer's disease?

Bhushan I, Kour M, Kour G, Gupta S, Sharma S, Yadav A. Alzheimer’s disease: Causes & treatment – A review. Annals of Biotechnology. 2018; 1(1): 1002.

Nussbaum RL, Ellis CE. Alzheimer’s disease and Parkinson’s disease. The New England Journal of Medicine. 2003; 348(14), 1356–1364. https://doi.org/10.1056/NEJM2003ra020003

Mistridis P, Krumm S, Monsch AU, Berres M, Taylor KI. The 12 Years Preceding Mild Cognitive Impairment Due to Alzheimer’s Disease: The Temporal Emergence of Cognitive Decline. Journal of Alzheimer’s disease: JAD. 2015; 48(4), 1095–1107. https://doi.org/10.3233/JAD-150137

Querfurth HW, LaFerla FM. Alzheimer’s disease. The New England Journal of Medicine. 2010; 362(4), 329–344. https://doi.org/10.1056/NEJMra0909142

Ribas MZ, Paticcié GF, Noleto FM, et al. Impact of dysexecutive syndrome in quality of life in Alzheimer disease: What we know now and where we are headed. Ageing Res Rev. 2023; 86:101866. https://doi.org/10.1016/j.arr.2023.101866

Suzuki Y, Sa Q, Ochiai E, Mullins J, Yolken R, Halonen SK. Cerebral Toxoplasmosis: Pathogenesis, Host Resistance and Behavioural

Consequences. Toxoplasma gondii (Second Edition), 2013; 755–796. https://doi.org/10.1016/B978-0-12-396481-6.00023-4

Koseoglu E, Yazar S, Koc I. Is Toxoplasma gondii a causal agent in migraine? The American Journal of the Medical Sciences,. 2009; 338(2), 120–122. https://doi.org/10.1097/MAJ.0b013e31819f8cac

Kaushik M, Lamberton PH, Webster JP. The role of parasites and pathogens in influencing generalised anxiety and predation-related fear in the mammalian central nervous system. Hormones and Behavior. 2012; 62(3), 191–201. https://doi.org/10.1016/j.yhbeh.2012.04.002

Jung BK, Pyo KH, Shin KY, et al. Toxoplasma gondii infection in the brain inhibits neuronal degeneration and learning and memory impairments in a murine model of Alzheimer’s disease. PLoS One. 2012;7(3):e33312. https://doi.org/10.1371/journal.pone.0033312

Nayeri T, Sarvi S, Sharif M, Daryani A. Toxoplasma gondii: A possible etiologic agent for Alzheimer’s disease. Heliyon. 2021;7(6):e07151. https://doi.org/10.1016/j.heliyon.2021.e07151

Bouscaren N, Pilleron S, Mbelesso P, et al. Prevalence of toxoplasmosis and its association with dementia in older adults in Central Africa: a result from the EPIDEMCA programme. Trop Med Int Health. 2018; 23(12):1304–1313. https://doi.org/10.1111/tmi.13151

Yang HY, Chien WC, Chung CH, et al. Risk of dementia in patients with toxoplasmosis: a nationwide, population-based cohort study in Taiwan. Parasit Vectors. 2021; 14(1):435. https://doi.org/10.1186/s13071-021-04928-7

Henriquez SA, Brett R, Alexander J, Pratt J, Roberts CW. Neuropsychiatric disease and Toxoplasma gondii infection. Neuroimmunomodulation. 2009; 16(2):122–133. https://doi.org/10.1159/000180267

McConkey GA, Martin HL, Bristow GC, Webster JP. Toxoplasma gondii infection and behaviour - location, location, location?. The Journal of Experimental Biology. 2013; 216(Pt 1), 113–119. https://doi.org/10.1242/jeb.074153

Perry CE, Gale SD, Erickson L, et al. Seroprevalence and Serointensity of Latent Toxoplasma gondii in a Sample of Elderly Adults With and Without Alzheimer Disease. Alzheimer Dis Assoc Disord. 2016;30(2):123–126. https://doi.org/10.1097/WAD.0000000000000108

Mahami-Oskouei M, Hamidi F, Talebi M, et al. Toxoplasmosis and Alzheimer: can Toxoplasma gondii really be introduced as a risk factor in etiology of Alzheimer?. Parasitol Res. 2016; 115(8):3169–3174. https://doi.org/10.1007/s00436-016-5075-5