Dosimetric Comparison of Oncentra (Ir-192) and SagiPlan (Co-60) HDR Brachytherapy Planning Systems in Gynaecologic Tumors Using Different Applicator Sizes

Authors

  • Sura Yosif Physics Department, Faculty of Science, Mansoura University, Mansoura 35516, Egypt; Warith International Cancer Institution, Al-Horr Road, Karbala, Iraq.
  • Maha Kamaleldin Department of Medical Physics, Kasr Al-Ainy Center of Clinical Oncology & Nuclear Medicine, Kasr Al-Ainy School of Medicine, Cairo University, Cairo, Egypt.
  • Haydar H. Alabedi Warith International Cancer Institution, Al-Horr Road, Karbala, Iraq; College of Medicine, University of Baghdad, Baghdad, Iraq.
  • Salim T. El-Basyouny Physics Department, Faculty of Science, Mansoura University, Mansoura 35516, Egypt.
  • Mohammed Sallah Department of Physics, College of Sciences, University of Bisha, Bisha 61922, Saudi Arabia.
  • Elmetwally M. Abdelrazek Physics Department, Faculty of Science, Mansoura University, Mansoura 35516, Egypt.
  • Elmetwally M. Abdelrazek Physics Department, Faculty of Science, Mansoura University, Mansoura 35516, Egypt.

DOI:

https://doi.org/10.22317/jcms.v11i4.1972

Keywords:

HDR Brachytherapy, Oncentra, SagiPlan, gynecological tumors

Abstract

Objective: This study aims to compare the dosimetric outcomes of high-dose-rate (HDR) brachytherapy plans using Co-60 and Ir-192 sources implemented through SagiPlan and Oncentra treatment planning systems (TPS), respectively, across different applicator volumes.

Methods: CT-based HDR brachytherapy plans were developed using both SagiPlan (Co-60) and Oncentra (Ir-192) TPS for 30 cervical cancer patients. Applicator sizes of 35 cm³, 30 cm³, and 25 cm³ were evaluated. Dosimetric parameters including D90% (dose covering 90% of HR-CTV), conformity index (CI), and organ-at-risk (OAR) doses were analyzed. Total Reference Air Kerma (TRAK) was also assessed.

Results: Oncentra (Ir-192) showed improved D90% values with decreasing applicator size: 93.05% (35 cm³), 97.03% (30 cm³), and 96.35% (25 cm³). Conversely, SagiPlan (Co-60) D90% declined from 96.15% to 89.71%. CI was higher with Oncentra (0.72 vs. 0.68 average). OAR sparing was consistently better with Oncentra, with rectal D2cc reduced by up to 5%. TRAK values were similar between systems.

Conclusion: Ir-192 plans generated by Oncentra provide improved target coverage and OAR sparing in smaller applicators compared to Co-60 plans using SagiPlan. These findings emphasize the importance of source selection and TPS capabilities in optimizing brachytherapy outcomes

Author Biographies

Maha Kamaleldin, Department of Medical Physics, Kasr Al-Ainy Center of Clinical Oncology & Nuclear Medicine, Kasr Al-Ainy School of Medicine, Cairo University, Cairo, Egypt.

 

 

Haydar H. Alabedi, Warith International Cancer Institution, Al-Horr Road, Karbala, Iraq; College of Medicine, University of Baghdad, Baghdad, Iraq.

 

 

Salim T. El-Basyouny, Physics Department, Faculty of Science, Mansoura University, Mansoura 35516, Egypt.

 

 

Mohammed Sallah, Department of Physics, College of Sciences, University of Bisha, Bisha 61922, Saudi Arabia.

 

 

Elmetwally M. Abdelrazek, Physics Department, Faculty of Science, Mansoura University, Mansoura 35516, Egypt.

 

 

Elmetwally M. Abdelrazek, Physics Department, Faculty of Science, Mansoura University, Mansoura 35516, Egypt.

 

 

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Published

2025-08-26

How to Cite

Yosif, S., Kamaleldin, M., Alabedi, H. H., El-Basyouny, S. T., Sallah, M., Abdelrazek, E. M., & Abdelrazek, E. M. (2025). Dosimetric Comparison of Oncentra (Ir-192) and SagiPlan (Co-60) HDR Brachytherapy Planning Systems in Gynaecologic Tumors Using Different Applicator Sizes. Journal of Contemporary Medical Sciences, 11(4). https://doi.org/10.22317/jcms.v11i4.1972

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Vol. 11 No. 4 (2025): July-August

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