Clinicopathological Characteristics and Treatment Outcomes of Bone and Soft Tissue Tumors
DOI:
https://doi.org/10.22317/jcms.v12i1.2067Keywords:
Bone Neoplasms, Soft Tissue Neoplasms , Disease Attributes , Treatment Outcome , Saudi ArabiaAbstract
Objectives: To delineate the clinicopathological characteristics of bone tumors (BT) and soft tissue tumors (STT) and to evaluate management outcomes.
Methods: A retrospective cross-sectional analysis was performed on patients diagnosed with BT and STT between 2020 and 2025. Tumor characteristics and treatment outcomes were assessed and compared.
Results: A total of 359 patients (median age, 32 years; 50.7% male) were included. BT accounted for 163 cases (45.4%), while 196 (54.6%) were STT. Osteochondroma represented the most common BT (37.4%), whereas lipoma was the most frequent STT (30.6%). Patients with BT were younger (median age, 22 years) and predominantly male, whereas STT patients were older (median age, 43 years) with female predominance. Malignancy was more frequent among STT compared with BT (26.5% vs 13.5%, p=0.002). Radiotherapy was administered more often in STT than BT (13.3% vs 3.7%, p=0.002). Mortality occurred in two BT patients (1.2%). No significant differences in overall management outcomes were observed between groups.
Conclusion: The clinical profile of BT and STT in this Saudi cohort aligns with published data, although variations in age distribution and sex predominance were observed. Mortality rates were low for both BT (1.2%) and STT (2.0%). Constitutional manifestations, such as unexplained weight loss and progressive fatigue, may heighten suspicion of malignancy, particularly in the presence of a mass and localized bone symptoms. Strengthening early detection strategies and adopting multidisciplinary management pathways may improve diagnostic accuracy and optimize sarcoma care.
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