Effect of Early Initiation of Combination Therapy of Anti-Inflammatory and Anti-Fibrotic Drugs on Post COVID-19 Interstitial Lung Disease: A Case Report

Authors

  • Rahmah Alsilmi Division of Pulmonology, Department of Internal Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia. http://orcid.org/0000-0001-9396-1174

DOI:

https://doi.org/10.22317/jcms.v7i3.987

Keywords:

Case report, COVID-19, pirfenidone, anti-fibrotic, systemic corticosteroid, macrolide

Abstract

The persistence of lung parenchymal changes Post COVID-19 is increasingly recognized as a vital outcome observed on some patients recovering from SARS-CoV2 infection with limited evidence-based management so far. Here we present a 64-year-old male developed extensive interstitial lung changes post SARS-CoV2 infection and was successfully managed with oral prednisone, pirfenidone, and azithromycin maintenance regimen with significant improvement in his clinical and radiographic parameters noted within a relatively short time. The role of a combined therapeutic approach with anti-inflammatory and anti-fibrotic drugs might be provocative action in patients with COVID-19 related interstitial lung disease, especially those at risk for persistent long-term abnormalities and pulmonary fibrosis development. 

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Published

2021-06-26

How to Cite

Alsilmi, R. (2021). Effect of Early Initiation of Combination Therapy of Anti-Inflammatory and Anti-Fibrotic Drugs on Post COVID-19 Interstitial Lung Disease: A Case Report. Journal of Contemporary Medical Sciences, 7(3), 189–191. https://doi.org/10.22317/jcms.v7i3.987

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Section

Case Report