A study of the Incidence of Cytomegalovirus infection and Preemptive Therapy in Kidney Transplant Recipients

Authors

  • Zana Sidiq M Saleem Department of Internal Medicine, College of Medicine, University of Duhok, Duhok, Iraq.
  • Kais H Abd Duhok Renal Dialysis and organ transplant Center, Duhok, Kurdistan Region, Iraq.
  • Nashwan M.R. Ibrahim Department of Surgery, College of Medicine, University of Duhok, Duhok, Iraq.
  • Nawfal R Hussein Department of Medicine, College of Medicine, University of Zakho, Zakho, Kurdistan region, Iraq.
  • Hasanain MA Al-Khammas Basrah Center for Kidney Disease and Renal Transplant center, Ministry of Health, Basrah, Iraq.

DOI:

https://doi.org/10.22317/jcms.v8i1.1125

Keywords:

CMV; Preemptive; Iraq; kidney; transplant

Abstract

Objectives: This project aimed to determine the incidence of CVM infection and evaluate the outcome of preemptive treatment.

Methods: This prospective, two centers cohort study included recipients who underwent renal transplant between May 2019-May 2020. The incidence of CMV infection and graft outcomes were studied. All managed with preemptive therapy.

Results: In this study, 134 renal transplant recipients were recruited. Among them, 30/134 (22.4%) patients tested positive for CMV-RTPCR. We studied the impact of age on the CMV-positivity and we found that the age of the doner was associated with CMV-positivity (P= 0.025; OR= 0.923; CI= 0.8584-0.9943). Smoking and gender showed no association with CMV-positivity.

Conclusions: our data suggest that the course of CMV infection is benign with a high success rate of preemptive treatment. Further evaluation for the universal prophylactic plan is needed.

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Published

2022-02-26

How to Cite

M Saleem, Z. S., H Abd, K. ., Ibrahim, N. M. ., Hussein, N. R. ., & Al-Khammas, H. M. (2022). A study of the Incidence of Cytomegalovirus infection and Preemptive Therapy in Kidney Transplant Recipients. Journal of Contemporary Medical Sciences, 8(1), 44–46. https://doi.org/10.22317/jcms.v8i1.1125